SCHEMBL30998138

SCHEMBL30998138

O=C(Nc1cccnc1)c1cc(Cl)c(Cl)cc1F

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 7/20 0.77
CYP11B1 P15538 4/20 0.77
CSF1R P07333 4/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
LMNA P02545 2/20 0.60
KCNMA1 Q12791 1/20 0.60
TP53 P04637 1/20 0.60
HTT P42858 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.57
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55
NPC1 O15118 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29131430 0.82 GRM5 (0.54) CYP11B2CYP11B1KMT2ALMNASMN1; SMN2
SCHEMBL3933275 0.81 CSF1R (0.72) CYP11B2CYP11B1CSF1RMEN1KMT2A
SCHEMBL31171365 0.80 CYP11B2 (0.71) CYP11B2CYP11B1MEN1KMT2ALMNA
SCHEMBL14083581 0.80 CYP11B2 (0.67) CYP11B2CYP11B1CSF1RMEN1KMT2A
SCHEMBL8224938 0.80 CYP11B2 (0.72) CYP11B2CYP11B1MEN1KMT2ALMNA
SCHEMBL14094289 0.80 JAK2 (0.71) CYP11B2CYP11B1CSF1RMEN1KMT2A
SCHEMBL3940427 0.80 CYP11B2 (0.71) CYP11B2CYP11B1CSF1RMEN1KMT2A
SCHEMBL4878207 0.80 CYP11B2 (0.72) CYP11B2CYP11B1MEN1KMT2ALMNA
SCHEMBL3936478 0.78 CSF1R (0.81) CYP11B2CYP11B1CSF1RMEN1KMT2A
SCHEMBL15058890 0.78 CYP11B2 (0.66) CYP11B2CYP11B1CSF1RMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024153856-A1 PROCESS FOR THE PREPARATION OF 3-(4,5-DICHLORO-2-(4-(TRIFLUOROMETHOXY)PHENOXY)BENZAMIDO)PYRIDINE 1-OXIDE ORION CORPORATION (FI) 2024-07-25 WO claimed
WO-2024153856-A1 PROCESS FOR THE PREPARATION OF 3-(4,5-DICHLORO-2-(4-(TRIFLUOROMETHOXY)PHENOXY)BENZAMIDO)PYRIDINE 1-OXIDE ORION CORPORATION (FI) 2024-07-25 WO disclosed