Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878207 | 0.84 | CYP11B2 (0.72) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL23099978 | 0.82 | CYP11B2 (0.69) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL31171365 | 0.81 | CYP11B2 (0.71) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL8611362 | 0.81 | CYP11B2 (0.67) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL12078267 | 0.81 | CYP11B2 (0.67) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL30998138 | 0.80 | CYP11B2 (0.77) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL13162555 | 0.77 | CYP11B2 (0.77) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL13161983 | 0.77 | CYP11B2 (0.77) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL31171339 | 0.76 | LMNA (0.71) | CYP11B2CYP11B1LMNAMEN1KMT2A | |
| SCHEMBL14083581 | 0.76 | CYP11B2 (0.67) | CYP11B2CYP11B1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004117-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-01-10 | — | — | WO | disclosed |