Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31739854 | 0.87 | ALDH1A1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL31000137 | 0.82 | APLNR (0.32) | ALDH1A1LMNAAPLNR | |
| SCHEMBL24542801 | 0.82 | PDE10A (0.37) | ALDH1A1LMNA | |
| SCHEMBL31000179 | 0.81 | TRPC6 (0.40) | MAOA | |
| SCHEMBL30698321 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL31000173 | 0.76 | PRKAB2 (0.34) | ALDH1A1LMNA | |
| SCHEMBL15633193 | 0.75 | — | — | |
| SCHEMBL31000259 | 0.70 | PTAFR (0.33) | ALDH1A1LMNAAPLNR | |
| SCHEMBL31000097 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL31000267 | 0.69 | ENPP1 (0.36) | MAOAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |