Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000193 | 0.77 | CHRM5 (0.34) | ACVR2ATGFBR2LRRK2SHBG | |
| SCHEMBL31000263 | 0.75 | FYN (0.32) | ACVR2ATGFBR2LRRK2 | |
| SCHEMBL31639341 | 0.73 | PDE10A (0.34) | ACVR2ATGFBR2LRRK2 | |
| SCHEMBL31639231 | 0.70 | HPGD (0.34) | ACVR2ATGFBR2LRRK2 | |
| SCHEMBL31639301 | 0.69 | KDM4E (0.34) | — | |
| SCHEMBL31639289 | 0.68 | KDM4E (0.36) | — | |
| SCHEMBL31639434 | 0.66 | KDM4E (0.32) | — | |
| SCHEMBL30632316 | 0.64 | JUND (0.34) | ACVR2ATGFBR2 | |
| SCHEMBL31000135 | 0.63 | TRPC6 (0.41) | SHBG | |
| SCHEMBL30698321 | 0.63 | ALDH1A1 (0.33) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |