SCHEMBL31001665

SCHEMBL31001665

COc1c(NC(=O)c2ccc(I)cc2N2CCC3(CC2)CC3)cccc1N1CCC(F)(F)CC1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31463589 0.81 KIF18A (0.53) KIF18A
SCHEMBL30842152 0.79 KIF18A (0.52) KIF18A
SCHEMBL26151151 0.78 KIF18A (0.55) KIF18A
SCHEMBL31346971 0.78 KIF18A (0.49) KIF18A
SCHEMBL31463561 0.77 KIF18A (0.56) KIF18A
SCHEMBL31463507 0.77 KIF18A (0.50) KIF18A
SCHEMBL29578239 0.77 KIF18A (0.68) KIF18A
SCHEMBL22964659 0.77 KIF18A (0.68) KIF18A
SCHEMBL31001661 0.76 KIF18A (0.46) KIF18A
SCHEMBL30668866 0.76 KIF18A (0.48) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146593-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 浙江海正药业股份有限公司 2024-07-11 — — WO disclosed
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