Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL31004938 | 0.88 | JAK3 (0.36) | TYK2JAK2JAK3 | |
| SCHEMBL31004944 | 0.84 | TYK2 (0.64) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL31004926 | 0.75 | SMARCA2 (0.41) | JAK2JAK3 | |
| SCHEMBL31004946 | 0.73 | TYK2 (0.65) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL31004937 | 0.71 | TYK2 (0.65) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL31004924 | 0.67 | TYK2 (0.68) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL20140942 | 0.66 | CKS1B (0.49) | JAK2JAK3 | |
| SCHEMBL23900166 | 0.66 | TYK2 (0.69) | TYK2JAK2JAK1STAT3STAT1 | |
| SCHEMBL15933643 | 0.65 | GPR119 (0.45) | — | |
| SCHEMBL23899828 | 0.65 | TYK2 (0.80) | TYK2JAK2JAK1STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174229-A1 | COVALENT BINDING COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-08-29 | — | — | WO | disclosed |