Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31004951 | 0.80 | SMARCA2 (0.45) | SMARCA2SMARCA4PBRM1PARP1TNKS2 | |
| SCHEMBL20140942 | 0.78 | CKS1B (0.49) | MAPTMAPK1ADORA1JAK2JAK3 | |
| Zinc Ion SCHEMBL31004938 | 0.78 | JAK3 (0.36) | MAPTJAK2JAK3PTK2C5AR1 | |
| SCHEMBL24689567 | 0.76 | NR1H2 (0.43) | NR1H2C5AR1 | |
| Zinc Ion SCHEMBL31004935 | 0.75 | TYK2 (0.46) | JAK2JAK3 | |
| SCHEMBL15933697 | 0.75 | GPR119 (0.47) | NR1H2MAPK1POLB | |
| SCHEMBL15933643 | 0.75 | GPR119 (0.45) | NR1H2MAPTMAPK1 | |
| SCHEMBL15933537 | 0.74 | GBA1 (0.55) | NR1H2MAPK1ADORA2APOLB | |
| SCHEMBL28671907 | 0.72 | SRC (0.40) | SMARCA2SMARCA4PBRM1JAK3 | |
| SCHEMBL31612680 | 0.72 | HDAC4 (0.48) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174229-A1 | COVALENT BINDING COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-08-29 | — | — | WO | disclosed |