Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028832 | 0.89 | KMT2A (0.42) | MAPTKMT2AMEN1GAATDP1 | |
| SCHEMBL6243535 | 0.82 | MAPT (0.44) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL12694260 | 0.80 | L3MBTL1 (0.43) | MAPTKMT2AMEN1HDAC8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8038931 | 0.79 | MAPT (0.43) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL16746567 | 0.79 | CA2 (0.43) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL3109789 | 0.77 | ALDH1A1 (0.44) | MAPTLMNASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL560649 | 0.76 | EGFR (0.41) | MAPTGAAALDH1A1POLB | |
| SCHEMBL15665690 | 0.76 | GSTP1 (0.47) | MAPTKMT2AMEN1GAAPOLB | |
| SCHEMBL2006984 | 0.75 | KMT2A (0.41) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL1099561 | 0.74 | ALDH1A1 (0.52) | MAPTKMT2AMEN1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211705-B2 | Electrical detection and quantification of mercuric derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-07-03 | — | — | US | disclosed |
| US-8211705-B2 | Electrical detection and quantification of mercuric derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-07-03 | — | — | US | disclosed |
| US-8211705-B2 | Electrical detection and quantification of mercuric derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20100255593-A1 | Electrical Detection and Quantification of Mercuric Derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE | 2010-10-07 | — | — | US | disclosed |
| US-20100255593-A1 | Electrical Detection and Quantification of Mercuric Derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE | 2010-10-07 | — | — | US | disclosed |
| US-20100255593-A1 | Electrical Detection and Quantification of Mercuric Derivatives | COMMISSARIAT A L'ENERGIE ATOMIQUE | 2010-10-07 | — | — | US | disclosed |
| EP-2230510-A1 | Electrical detection and quantification of mercury derivatives | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2010-09-22 | — | — | EP | disclosed |
| US-20100152338-A1 | NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE | NITTO DENKO CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| WO-2008109701-A1 | NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE | NITTO DENKO CORPORATION (JP) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152338-A1 | NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE | C5, OR10J3, C1S | MAPT 4593/4885KMT2A 1960/4885MEN1 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.