Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31010032 | 0.86 | HPGD (0.50) | KMT2AMEN1BRCA1IDO1ALDH1A1 | |
| SCHEMBL20804137 | 0.69 | L3MBTL1 (0.61) | KMT2AMEN1BRCA1ALDH1A1HPGD | |
| SCHEMBL16069693 | 0.68 | SMN1; SMN2 (0.40) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL16334494 | 0.68 | CYP1A2 (0.42) | IDO1HPGDL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL17045823 | 0.68 | LMNA (0.42) | KMT2AMEN1BRCA1IDO1ALDH1A1 | |
| SCHEMBL25270599 | 0.67 | MAPT (0.55) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7651344 | 0.67 | HSP90AA1 (0.51) | KMT2AMEN1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL26830072 | 0.67 | KMT2A (0.49) | KMT2AMEN1BRCA1ALDH1A1HPGD | |
| SCHEMBL16334121 | 0.67 | CYP1A2 (0.41) | IDO1ALDH1A1HPGDL3MBTL1MAPT | |
| SCHEMBL5450459 | 0.66 | MAPT (0.47) | KMT2AMEN1ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648763-A2 | COMPOUNDS FOR FGFRS INHIBITORS | Cogent Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |