Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 1/20 | 0.44 |
| ▸ | STK3 | Q13188 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 9/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31013258 | 0.79 | SMN1; SMN2 (0.44) | SCN10A | |
| SCHEMBL31013248 | 0.79 | PIK3CA (0.37) | STK4STK3PTPN11PIK3CAMTOR | |
| SCHEMBL22587541 | 0.78 | ALDH1A1 (0.49) | — | |
| SCHEMBL31013290 | 0.77 | ALDH1A1 (0.51) | STK4STK3 | |
| SCHEMBL22597991 | 0.73 | OPRK1 (0.44) | PIK3CAMTORATRPDE10AMDM2 | |
| SCHEMBL29445465 | 0.73 | OPRK1 (0.44) | PIK3CAMTORATRPDE10AMDM2 | |
| SCHEMBL3435695 | 0.71 | CYP3A4 (0.52) | MDM2 | |
| SCHEMBL14334648 | 0.71 | HRH3 (0.43) | PTPN11 | |
| SCHEMBL2273098 | 0.70 | LMNA (0.55) | ATRMDM2 | |
| SCHEMBL22587534 | 0.70 | PIK3CA (0.45) | PIK3CAMTORPDE10AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646263-A1 | SPRK1 INHIBITORS AND METHODS OF USE | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024155864-A1 | SPRK1 INHIBITORS AND METHODS OF USE | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |