Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31013255 | 0.82 | SCN10A (0.47) | SMN1; SMN2LMNASCN10APOLBMAPT | |
| SCHEMBL31013298 | 0.81 | CXCR3 (0.53) | SMN1; SMN2LMNASCN10APOLBMAPT | |
| SCHEMBL31013268 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAPOLBMAPTTP53 | |
| SCHEMBL31013264 | 0.79 | STK4 (0.44) | SCN10A | |
| SCHEMBL31013248 | 0.76 | PIK3CA (0.37) | — | |
| SCHEMBL31410510 | 0.73 | MEN1 (0.56) | SMN1; SMN2LMNAMAPTHPGDHTT | |
| SCHEMBL31013294 | 0.73 | MAPT (0.55) | SMN1; SMN2LMNASCN10APOLBMAPT | |
| SCHEMBL31410462 | 0.73 | MEN1 (0.56) | SMN1; SMN2LMNAMAPTHPGDHTT | |
| SCHEMBL29818411 | 0.71 | NOS3 (0.39) | SMN1; SMN2LMNAPOLBMAPTTP53 | |
| SCHEMBL26608234 | 0.71 | SCN10A (0.49) | SMN1; SMN2LMNASCN10APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646263-A1 | SPRK1 INHIBITORS AND METHODS OF USE | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024155864-A1 | SPRK1 INHIBITORS AND METHODS OF USE | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |