Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.52 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080354 | 0.87 | KMT2A (0.50) | ALDH1A1KMT2AHPGDMEN1CYP2C19 | |
| SCHEMBL3104338 | 0.86 | LSS (0.52) | ALDH1A1KMT2AMEN1CYP2C19CYP2D6 | |
| SCHEMBL3102395 | 0.84 | SMN1; SMN2 (0.52) | ALDH1A1KMT2AHPGDMEN1CYP2C19 | |
| SCHEMBL3101764 | 0.83 | MAPK1 (0.62) | ALDH1A1KMT2AHPGDMEN1CYP2C19 | |
| SCHEMBL3104041 | 0.83 | SMN1; SMN2 (0.51) | ALDH1A1KMT2AHPGDMEN1CYP2C19 | |
| SCHEMBL3099738 | 0.83 | KDM4E (0.53) | ALDH1A1KMT2AMEN1CYP2C19TET3 | |
| SCHEMBL3097606 | 0.82 | TSHR (0.58) | ALDH1A1KMT2AHPGDMEN1CYP2C19 | |
| SCHEMBL3104290 | 0.82 | KMT2A (0.54) | ALDH1A1KMT2AMEN1CYP2C19CYP1A2 | |
| SCHEMBL13092183 | 0.81 | CYP2D6 (0.48) | ALDH1A1KMT2AHPGDMEN1CYP2C19 | |
| SCHEMBL3110127 | 0.81 | POLB (0.52) | ALDH1A1KMT2AHPGDMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324250-B2 | Piperidine derivatives as NK3 receptor antagonists | HOFFMANN-LA ROCHE INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100256126-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | HOFFMANN-LA ROCHE, INC. | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256126-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | HTR3A, OPRL1, OPRK1 | ALDH1A1 480/4885KMT2A 1488/4885HPGD 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.