Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.57 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.57 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002652 | 0.88 | CA12 (0.69) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL30536599 | 0.88 | CA12 (0.69) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL5710937 | 0.87 | HTT (0.51) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL6536225 | 0.86 | ALDH1A1 (0.51) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL6634531 | 0.85 | CA12 (0.55) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL7755637 | 0.85 | CA12 (0.55) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL13228930 | 0.83 | HTT (0.62) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| SCHEMBL27717648 | 0.83 | HTT (0.51) | FGFR1SRCFGFR2FGFR4FGFR3 | |
| Methyl 2,6-Dimethoxybenzoate SCHEMBL2095636 | 0.83 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9049651 | 0.83 | CA12 (0.69) | FGFR1SRCFGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525025-A | Six-membered cyclothiazole compound and application thereof | 南京再明医药有限公司 | 2024-08-20 | — | — | CN | disclosed |