SCHEMBL5710937

SCHEMBL5710937

COC(=O)c1c(OC(=O)O)cccc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.50
PRKCZ Q05513 1/20 0.50
GABRA1 P14867 1/20 0.49
GABRG2 P18507 1/20 0.49
GABRB3 P28472 1/20 0.49
GABRA5 P31644 1/20 0.49
GABRA3 P34903 1/20 0.49
FGFR1 P11362 3/20 0.48
FGFR2 P21802 3/20 0.48
FGFR4 P22455 3/20 0.48
FGFR3 P22607 3/20 0.48
SRC P12931 2/20 0.48
SLC6A3 Q01959 3/20 0.47
SLC6A4 P31645 2/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31019062 0.87 FGFR1 (0.57) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL27570075 0.85 ALDH1A1 (0.50) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL2873451 0.83 SLC6A3 (0.44) HTTALDH1A1FGFR1FGFR2FGFR4
SCHEMBL27552849 0.83 HTT (0.51) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL13228930 0.81 HTT (0.62) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL69682 0.80 SLC6A3 (0.57) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL9049651 0.80 CA12 (0.69) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL4827133 0.80 HTT (0.58) HTTMEN1KMT2ALMNAALDH1A1
Biphenyl SCHEMBL6812918 0.80 SLC6A3 (0.68) HTTKMT2ALMNAALDH1A1HPGD
SCHEMBL27552871 0.80 HTT (0.45) HTTMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103221484-A Automotive lamp extension molding ASAHI KASEI CHEMICALS CORP (JP) 2013-07-24 CN disclosed
CN-101056939-A Resin composition and flat panel display fixing frame TEIJIN CHEMICALS LTD (JP) 2007-10-17 CN disclosed
EP-1448661-B1 REDUCTION OF REACTION BY-PRODUCTS IN POLYCARBONATE RESINS GEN ELECTRIC (US) 2006-11-29 EP disclosed
CN-1280335-C Method for reducing reaction by-products in polycarbonate resins GEN ELECTRIC (US) 2006-10-18 CN disclosed
CN-1610716-A Reduction of reaction by-products in polycarbonate resins GEN ELECTRIC (US) 2005-04-27 CN disclosed
EP-1448661-A1 REDUCTION OF REACTION BY-PRODUCTS IN POLYCARBONATE RESINS GENERAL ELECTRIC COMPANY (US) 2004-08-25 EP disclosed
US-6590068-B2 Mixing scavengers such as 2-carbomethoxy-phenyl-2-naphthoate as by-product inhibitors in condensation polymerization of bisphenol A and diphenyl carbonate GENERAL ELECTRIC COMPANY 2003-07-08 US disclosed
US-20030100704-A1 REDUCTION OF REACTION BY-PRODUCTS IN POLYCARBONATE RESINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-05-29 US disclosed
WO-2003042279-A1 REDUCTION OF REACTION BY-PRODUCTS IN POLYCARBONATE RESINS GENERAL ELECTRIC COMPANY (US) 2003-05-22 WO disclosed