Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463088 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL2461447 | 0.88 | MAOA (0.56) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL29446267 | 0.85 | TACR2 (0.62) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL584489 | 0.85 | TACR2 (0.62) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL16838745 | 0.85 | MAOA (0.57) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL413789 | 0.85 | TACR2 (0.67) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL23178772 | 0.84 | RAB9A (0.46) | ALDH1A1POLBKMT2AERN1SMN1; SMN2 | |
| SCHEMBL5216251 | 0.83 | TACR2 (0.57) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL5217272 | 0.83 | TACR2 (0.57) | ALDH1A1MAOAMAOBPOLBMEN1 | |
| SCHEMBL29817001 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAOAMAOBPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994152-A | Integrin targeting ligands and uses thereof | 箭头药业股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-112074290-B | Integrin targeting ligands and uses thereof | 箭头药业股份有限公司 | 2024-09-10 | — | — | CN | disclosed |