SCHEMBL31020750

SCHEMBL31020750

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 3/20 0.62
▸ OPRM1 P35372 2/20 0.62
▸ CCKAR P32238 1/20 0.59
▸ CCKBR P32239 1/20 0.59
▸ KISS1R Q969F8 4/20 0.56
▸ IL1RN P18510 1/20 0.55
▸ ERAP2 Q6P179 1/20 0.55
▸ IL23R Q5VWK5 11/20 0.54
▸ PRMT1 Q99873 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29568760 0.92 IL1RN (0.61) OPRD1OPRM1CCKARCCKBRIL1RN
SCHEMBL30148136 0.89 OPRD1 (0.53) OPRD1OPRM1CCKARCCKBRKISS1R
SCHEMBL30622601 0.88 KISS1R (0.58) KISS1RIL23R
SCHEMBL31090170 0.88 ACE (0.58) OPRD1OPRM1ERAP2PRMT1
SCHEMBL30503004 0.87 LTA4H (0.60) OPRD1OPRM1CCKARCCKBR
SCHEMBL25037250 0.87 OPRD1 (0.72) OPRD1OPRM1CCKARCCKBRKISS1R
SCHEMBL25037253 0.87 OPRD1 (0.72) OPRD1OPRM1CCKARCCKBRKISS1R
SCHEMBL29973046 0.87 KISS1R (0.62) OPRD1OPRM1KISS1RIL23R
SCHEMBL29842144 0.85 OPRD1 (0.63) OPRD1OPRM1CCKARCCKBRKISS1R
SCHEMBL31442261 0.85 OPRD1 (0.71) OPRD1OPRM1CCKARCCKBRKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847223-B2 ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME DARTMOUTH COLLEGE (US) 2025-04-09 — — EP disclosed
US-20250002584-A1 ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME DARTMOUTH COLLEGE (US) 2025-01-02 — — US disclosed
US-12065492-B2 Anti-B7-H6 antibody, fusion proteins, and methods of using the same THE TRUSTEES OF DARTMOUTH COLLEGE (US) 2024-08-20 — — US disclosed
CN-110511278-B Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof 达特茅斯大学理事会 2024-08-09 — — CN disclosed
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