Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 4/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254537 | 0.84 | RIPK2 (0.36) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL28048502 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL29478085 | 0.72 | RIPK2 (0.60) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL927048 | 0.72 | RIPK2 (0.60) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL31500084 | 0.70 | CHRNB4 (0.45) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL12567719 | 0.69 | CHRNB4 (0.41) | ALDH1A1KDR | |
| SCHEMBL16429194 | 0.66 | QPCT (0.48) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL21508018 | 0.66 | ALOX5AP (0.49) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL24366781 | 0.66 | FFAR1 (0.35) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL24233949 | 0.66 | FFAR1 (0.35) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772164-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118359603-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |