Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31021270 | 0.84 | ALDH1A1 (0.41) | RIPK2ALOX5APFEN1FASNPIK3CD | |
| SCHEMBL29388659 | 0.72 | ALDH1A1 (0.50) | RIPK2NPC1RAB9AALOX5APFEN1 | |
| SCHEMBL4054554 | 0.72 | ALDH1A1 (0.50) | RIPK2NPC1RAB9AALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL27261649 | 0.70 | ALDH1A1 (0.47) | RIPK2NPC1RAB9AALOX5APFEN1 | |
| SCHEMBL28048502 | 0.69 | ALDH1A1 (0.54) | RIPK2NPC1RAB9AALOX5APFEN1 | |
| SCHEMBL3311489 | 0.69 | DYRK1A (0.46) | RIPK2ALOX5APFEN1FASNTRPV3 | |
| SCHEMBL1851318 | 0.67 | TRPV3 (0.44) | RIPK2NPC1RAB9AALOX5APFEN1 | |
| SCHEMBL1854129 | 0.66 | CYP2A6 (0.45) | RIPK2ALOX5APFEN1FASNTRPV3 | |
| SCHEMBL31500084 | 0.66 | CHRNB4 (0.45) | RIPK2FASNEGFRKDRTGFBR1 | |
| SCHEMBL28357109 | 0.65 | PIK3CD (0.38) | RIPK2ALOX5APFEN1FASNTRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772164-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-10-15 | — | — | CN | disclosed |