Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986544 | 0.80 | MEN1 (0.37) | MEN1KMT2ATDP1 | |
| SCHEMBL31159341 | 0.77 | KDM4E (0.42) | ICAM1SELEMLYCDPIK3CAMTOR | |
| SCHEMBL17157497 | 0.77 | SIRT3 (0.54) | ICAM1SELEMLYCDTDP1 | |
| SCHEMBL1888272 | 0.77 | KDM4E (0.42) | ICAM1SELEMLYCDPIK3CAMTOR | |
| SCHEMBL24612469 | 0.75 | NNMT (0.40) | ICAM1SELEMLYCDPIK3CAMTOR | |
| SCHEMBL21530458 | 0.75 | PIK3CA (0.38) | ICAM1SELEPIK3CAMTORTRPM8 | |
| SCHEMBL3449251 | 0.73 | LMNA (0.42) | ICAM1SELEMLYCDPIK3CAMTOR | |
| SCHEMBL13164028 | 0.72 | TSHR (0.44) | KMT2ATDP1RAB9A | |
| SCHEMBL4611372 | 0.72 | KMT2A (0.53) | TRPM8MEN1KMT2ARAB9A | |
| SCHEMBL13265171 | 0.71 | MLYCD (0.40) | ICAM1SELEMLYCDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655069-A1 | PYRIDAZINES AS SARM1 INHIBITORS | Disarm Therapeutics, Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| EP-4655295-A1 | SUBSTITUTED 1H-PYRAZOLE-4-CARBOXAMIDES AS SARM1 INHIBITORS | Disarm Therapeutics, Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024158775-A1 | PYRIDAZINES AS SARM1 INHIBITORS | DISARM THERAPEUTICS, INC. (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024158607-A1 | SUBSTITUTED 1H-PYRAZOLE-4-CARBOXAMIDES AS SARM1 INHIBITORS | DISARM THERAPEUTICS, INC. (US) | 2024-08-02 | — | — | WO | disclosed |