Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31021996 | 0.84 | RORC (0.31) | MAPK1 | |
| SCHEMBL4145572 | 0.84 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL16619784 | 0.84 | CASP7 (0.31) | MAPK1 | |
| SCHEMBL16620464 | 0.79 | RXFP1 (0.39) | MAPK1 | |
| SCHEMBL30084144 | 0.79 | ELANE (0.34) | — | |
| SCHEMBL16213479 | 0.79 | TYMS (0.36) | MAPK1 | |
| SCHEMBL19100294 | 0.75 | CYP11B1 (0.33) | MAPK1 | |
| SCHEMBL19671757 | 0.73 | MAOA (0.36) | MAPK1 | |
| SCHEMBL28209997 | 0.73 | ACSS2 (0.35) | MAPK1 | |
| SCHEMBL31021936 | 0.73 | MAPK1 (0.34) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024158745-A1 | INHIBITORS OF LRRK2 | VANDERBILT UNIVERSITY (US) | 2024-08-02 | — | — | WO | disclosed |