Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706996 | 0.75 | IKBKB (0.34) | IKBKBHTR2AHTR2CACVR1TGFBR1 | |
| SCHEMBL14849195 | 0.70 | HTR2A (0.40) | HTR2AHTR2CACVR1TGFBR1 | |
| SCHEMBL9971963 | 0.69 | MGLL (0.41) | HTR2AHTR2CTGFBR1 | |
| SCHEMBL20748895 | 0.69 | TLR9 (0.42) | HTR2AHTR2CACVR1TGFBR1 | |
| SCHEMBL31707208 | 0.69 | HTR2A (0.32) | HTR2AHTR2C | |
| SCHEMBL19705565 | 0.68 | HTR2C (0.33) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL108798 | 0.68 | MGLL (0.41) | HTR2AHTR2CTGFBR1 | |
| SCHEMBL13867827 | 0.67 | GAA (0.46) | IKBKBHTR2AHTR2C | |
| SCHEMBL15432302 | 0.67 | TGFBR1 (0.37) | HTR2AHTR2CTGFBR1 | |
| SCHEMBL10025712 | 0.66 | SCN9A (0.33) | IKBKBHTR2AHTR2CTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |