Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631031 | 0.92 | ITGB3 (0.42) | NOD1ITGB3ITGA2BMAPK1SMN1; SMN2 | |
| SCHEMBL3625936 | 0.88 | NOD1 (0.50) | NOD1TGM2SIRT2SIRT1ITGB3 | |
| SCHEMBL3629433 | 0.87 | NOD1 (0.53) | NOD1SIRT2SIRT1EPHX1 | |
| SCHEMBL7382637 | 0.87 | NOD1 (0.48) | NOD1TGM2SIRT2SIRT1ITGB3 | |
| SCHEMBL1077922 | 0.87 | NOD1 (0.48) | NOD1TGM2SIRT2SIRT1ITGB3 | |
| SCHEMBL5970938 | 0.84 | ACHE (0.49) | NOD1TGM2SIRT2SIRT1ITGB3 | |
| SCHEMBL8973585 | 0.84 | NOD1 (0.55) | NOD1SIRT2SIRT1EPHX1 | |
| SCHEMBL3655323 | 0.84 | ITGB3 (0.46) | NOD1TGM2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL284211 | 0.84 | ITGB3 (0.46) | NOD1TGM2ITGB3ITGA2BALDH1A1 | |
| SCHEMBL283288 | 0.84 | ITGB3 (0.46) | NOD1TGM2ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118369325-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-19 | — | — | CN | disclosed |