Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023754 | 0.90 | ALDH1A1 (0.43) | MGLLCYP3A4ALDH1A1LMNAFAAH | |
| SCHEMBL31023722 | 0.85 | MGLL (0.49) | MGLLCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL31023784 | 0.84 | SMN1; SMN2 (0.48) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL28919139 | 0.81 | CYP3A4 (0.59) | CYP3A4 | |
| SCHEMBL31023691 | 0.79 | MGLL (0.45) | MGLLCYP3A4ALDH1A1LMNAFAAH | |
| SCHEMBL31023988 | 0.78 | HTR2C (0.43) | CYP3A4 | |
| SCHEMBL31023747 | 0.77 | SCD5 (0.51) | MGLLLMNAMAPTMEN1KMT2A | |
| SCHEMBL31023933 | 0.77 | MEN1 (0.55) | MGLLLMNAMAPTMEN1KMT2A | |
| SCHEMBL15094598 | 0.76 | MGLL (0.67) | MGLLALDH1A1LMNAFAAHMAPT | |
| SCHEMBL21722935 | 0.74 | CYP3A4 (0.47) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |