Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023978 | 0.90 | MGLL (0.47) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL31023784 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL31023933 | 0.84 | MEN1 (0.55) | LMNAMAPTKMT2APOLBMEN1 | |
| SCHEMBL28613535 | 0.81 | CYP3A4 (0.54) | ATMRAB9ANPC1KMT2ACYP3A4 | |
| SCHEMBL31023963 | 0.78 | CYP3A4 (0.43) | ALDH1A1TDP1LMNASMN1; SMN2MAPT | |
| SCHEMBL31023747 | 0.76 | SCD5 (0.51) | LMNAMAPTKMT2APOLBMEN1 | |
| SCHEMBL31023722 | 0.76 | MGLL (0.49) | MAPTKMT2ACYP3A4POLBMEN1 | |
| SCHEMBL28598203 | 0.75 | CCR5 (0.49) | NPC1KMT2ACYP3A4MEN1 | |
| SCHEMBL31023731 | 0.75 | MGLL (0.48) | KMT2AFAAHMGLL | |
| SCHEMBL31023799 | 0.73 | BMP1 (0.54) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |