Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660384 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL2891613 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL31024119 | 0.76 | — | — | |
| SCHEMBL30726705 | 0.75 | MPO (0.43) | — | |
| SCHEMBL29241951 | 0.75 | MPO (0.43) | — | |
| SCHEMBL5424020 | 0.75 | KMT2A (0.42) | CHRNA3CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL1890852 | 0.75 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL31296163 | 0.73 | CHRNA3 (0.46) | CHRNA3CHRNB2CHRNB4CHRNA7CHRNA4 | |
| SCHEMBL31026422 | 0.72 | NNMT (0.44) | CHRNB2CHRNA4LMNA | |
| SCHEMBL27770704 | 0.72 | AR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722211-A1 | FGFR2/3 SELECTIVE INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| WO-2025056068-A1 | BICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海济煜医药科技有限公司 | 2025-03-20 | — | — | WO | disclosed |
| WO-2024240231-A1 | FGFR2/3 SELECTIVE INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-11-28 | — | — | WO | disclosed |
| CN-115605467-A | PHD inhibitor compounds, compositions and uses thereof | 阿克比治疗有限公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-100408572-C | imidazole derivatives as glutamate receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | CN | disclosed |
| CN-1802367-A | Imidazole derivatives as glutmate receptor antagonists | HOFFMANN LA ROCHE (CH) | 2006-07-12 | — | — | CN | disclosed |