Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31025659 | 0.81 | TP53 (0.44) | ADORA3ADORA1POLBADORA2AHPGD | |
| SCHEMBL31025529 | 0.78 | NPC1 (0.33) | — | |
| SCHEMBL31025558 | 0.78 | TDP2 (0.30) | — | |
| SCHEMBL22987540 | 0.76 | TP53 (0.42) | ADORA3ADORA1XDHADORA2ATP53 | |
| SCHEMBL22987536 | 0.75 | AMY1A (0.44) | ADORA3MAPTKDM4EALDH1A1TP53 | |
| SCHEMBL31025518 | 0.74 | GABRP (0.57) | ADORA3POLBGABRPGABRDGABRA1 | |
| SCHEMBL22979023 | 0.73 | ADORA3 (0.69) | ADORA3ADORA1MAPTPOLBGABRP | |
| SCHEMBL29646414 | 0.73 | ADORA3 (0.69) | ADORA3ADORA1MAPTPOLBGABRP | |
| SCHEMBL22988116 | 0.72 | ADORA3 (0.53) | ADORA3ADORA1MAPTPOLBTP53 | |
| SCHEMBL22987774 | 0.68 | ADORA3 (0.45) | ADORA3ADORA1MAPTXDHADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658657-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Mirati Therapeutics, Inc. (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163707-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Mirati Therapeutics, Inc. (US) | 2024-08-08 | — | — | WO | disclosed |