Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30293255 | 0.72 | LMNA (0.39) | TSHRALDH1A1DRD2 | |
| SCHEMBL4299024 | 0.72 | KDM4E (0.41) | TSHRALDH1A1 | |
| SCHEMBL30293250 | 0.71 | GSK3A (0.42) | SIGMAR1TSHRALDH1A1 | |
| SCHEMBL3698883 | 0.71 | CA12 (0.37) | TSHRALDH1A1DRD2 | |
| SCHEMBL29496906 | 0.71 | ALOX5 (0.44) | MAOBALDH1A1 | |
| Iodide SCHEMBL29405935 | 0.71 | KDM4E (0.40) | TSHRALDH1A1 | |
| SCHEMBL1352936 | 0.71 | NOTUM (0.44) | TSHRALDH1A1 | |
| Iodide SCHEMBL28887683 | 0.71 | KDM4E (0.40) | TSHRALDH1A1 | |
| SCHEMBL28611007 | 0.69 | KDM4E (0.36) | TSHRALDH1A1 | |
| SCHEMBL28426315 | 0.69 | BRD4 (0.38) | LTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433124-B | Preparation method of 4-chloro-6-methoxy-7-benzyloxy quinoline | 常州佳德医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |