SCHEMBL31025901

SCHEMBL31025901

Cc1cc2c(C)c(C(=O)O)[nH]c2cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
KMT2A Q03164 1/20 0.48
GRIN1 Q05586 2/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
BCL2 P10415 3/20 0.43
MCL1 Q07820 3/20 0.43
GPR35 Q9HC97 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025927 0.89 MEN1 (0.50) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025891 0.85 GPR35 (0.51) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31125244 0.84 ALDH1A1 (0.44) MEN1ALDH1A1KMT2AGRIN1GRIN2D
SCHEMBL31025896 0.83 GPR35 (0.46) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025917 0.83 PTGS1 (0.48) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL22760218 0.82 MCL1 (0.46) BCL2MCL1
SCHEMBL9449371 0.82 KDM4E (0.56) BCL2MCL1
SCHEMBL31025898 0.81 MTNR1A (0.50) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL31025894 0.80 FASN (0.48) MEN1ALDH1A1POLBPKMNPY1R
SCHEMBL11784003 0.77 GPR35 (0.66) MEN1ALDH1A1POLBPKMNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
CN-118852145-A GSPT1 degradation agent and application thereof 南京圣和药业股份有限公司 2024-10-29 CN disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed