SCHEMBL31025922

SCHEMBL31025922

Cc1c(C(=O)O)[nH]c2cc(O)ccc12

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
HPGD P15428 2/20 0.54
GLA P06280 1/20 0.54
GAA P10253 1/20 0.54
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
POLB P06746 1/20 0.49
PKM P14618 1/20 0.49
NPY1R P25929 1/20 0.49
NPY2R P49146 1/20 0.49
EIF4A3 P38919 1/20 0.45
GPR35 Q9HC97 4/20 0.45
SMAD3 P84022 1/20 0.42
HTT P42858 1/20 0.42
GFER P55789 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GLI1 P08151 1/20 0.41
GLI2 P10070 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5962663 0.86 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDGAAMEN1
SCHEMBL6179303 0.85 KDM4E (0.49) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL1144752 0.84 MEN1 (0.54) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL1121564 0.81 KDM4E (0.59) ALDH1A1KDM4EHPGDGAAMEN1
SCHEMBL3033953 0.81 GPR35 (0.65) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL1144990 0.81 GPR17 (0.60) KDM4EHPGDMEN1KMT2A
SCHEMBL31025912 0.81 MEN1 (0.48) ALDH1A1KDM4EHPGDGAAMEN1
SCHEMBL31025889 0.81 EGFR (0.59) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL5023538 0.80 PRNP (0.58)
SCHEMBL31025893 0.78 KIF11 (0.58) ALDH1A1HPGDMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed