SCHEMBL31025912

SCHEMBL31025912

Cc1c(C(=O)O)[nH]c2cc(N)ccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 3/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
PARP1 P09874 1/20 0.46
EIF4A3 P38919 1/20 0.44
NGFR P08138 1/20 0.44
IMPDH2 P12268 1/20 0.42
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HTT P42858 1/20 0.41
GFER P55789 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
AR P10275 1/20 0.41
USP2 O75604 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8315715 0.86 ALDH1A1 (0.59) MEN1KMT2AALDH1A1POLBPKM
SCHEMBL28338744 0.84 KDM4E (0.48) MEN1KMT2AALDH1A1POLBPKM
SCHEMBL1144752 0.82 MEN1 (0.54) MEN1KMT2AALDH1A1POLBPKM
SCHEMBL31025922 0.81 ALDH1A1 (0.54) MEN1KMT2AALDH1A1POLBPKM
SCHEMBL1144990 0.79 GPR17 (0.60) MEN1KMT2AKDM4EHPGD
SCHEMBL31025889 0.79 EGFR (0.59) MEN1KMT2AALDH1A1POLBPKM
SCHEMBL31025893 0.77 KIF11 (0.58) MEN1KMT2AALDH1A1POLBPKM
SCHEMBL1144751 0.77 GPR17 (0.64) MEN1KMT2AALDH1A1POLBKDM4E
SCHEMBL7041828 0.76 IMPDH2 (0.56) MEN1KMT2AALDH1A1POLBPARP1
SCHEMBL31025910 0.76 MAPT (0.55) MEN1KMT2AALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed