SCHEMBL31025923

SCHEMBL31025923

Cc1c(C(=O)O)[nH]c2cc([N+](=O)[O-])c(O)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MEN1 O00255 2/20 0.59
POLB P06746 2/20 0.59
KMT2A Q03164 2/20 0.59
PKM P14618 1/20 0.59
NPY1R P25929 1/20 0.59
NPY2R P49146 1/20 0.59
GPR35 Q9HC97 7/20 0.45
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
NSD2 O96028 1/20 0.40
PLA2G1B P04054 1/20 0.40
PLCG1 P19174 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025909 0.87 ALDH1A1 (0.61) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL31025930 0.84 ALDH1A1 (0.58) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL31025886 0.82 ALDH1A1 (0.56) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL11784003 0.81 GPR35 (0.66) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL31025891 0.75 GPR35 (0.51) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL8985895 0.75 ALDH1A1 (0.78) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL6847834 0.75 ALDH1A1 (1.00) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL31025927 0.69 MEN1 (0.50) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL6183724 0.69 FBP1 (0.71) ALDH1A1MEN1POLBKMT2APKM
SCHEMBL2240139 0.68 TSHR (0.53) ALDH1A1MEN1KMT2AGPR35TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed