Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 12/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027424 | 0.91 | OPRD1 (0.41) | NAMPTGPR119KITOPRD1OPRK1 | |
| SCHEMBL25437390 | 0.80 | KIT (0.51) | NAMPTGPR119KITTNKSPARP1 | |
| SCHEMBL30406053 | 0.80 | KIT (0.51) | NAMPTGPR119KITTNKSPARP1 | |
| SCHEMBL31027436 | 0.75 | NAMPT (0.41) | NAMPTKITCYP2C9 | |
| SCHEMBL31027396 | 0.74 | NAMPT (0.41) | NAMPTGPR119KIT | |
| SCHEMBL31027446 | 0.74 | NAMPT (0.41) | NAMPTGPR119CYP2C9 | |
| SCHEMBL30455937 | 0.71 | KIT (0.49) | KITOPRD1OPRK1TNKSPARP1 | |
| SCHEMBL25225988 | 0.71 | KIT (0.49) | KITOPRD1OPRK1TNKSPARP1 | |
| SCHEMBL31027420 | 0.70 | KIT (0.44) | NAMPTGPR119KITCYP2C9TNKS | |
| SCHEMBL16049766 | 0.68 | NAMPT (0.59) | NAMPTGPR119HDAC1HDAC6OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |