Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027427 | 0.91 | NAMPT (0.49) | OPRD1OPRK1KITNAMPTPARP1 | |
| SCHEMBL25225988 | 0.79 | KIT (0.49) | OPRD1OPRK1KITSLC2A1TLR9 | |
| SCHEMBL30455937 | 0.79 | KIT (0.49) | OPRD1OPRK1KITSLC2A1TLR9 | |
| SCHEMBL31027436 | 0.76 | NAMPT (0.41) | KITNAMPT | |
| SCHEMBL31027396 | 0.76 | NAMPT (0.41) | KITNAMPTGPR119 | |
| SCHEMBL31027446 | 0.75 | NAMPT (0.41) | NAMPTGPR119 | |
| SCHEMBL8218920 | 0.75 | GPR119 (0.48) | OPRD1OPRK1NAMPTGPR119TACR1 | |
| SCHEMBL31027420 | 0.71 | KIT (0.44) | KITNAMPTPARP1TNKSTNKS2 | |
| SCHEMBL25437390 | 0.70 | KIT (0.51) | KITNAMPTPARP1TNKSTNKS2 | |
| SCHEMBL30406053 | 0.70 | KIT (0.51) | KITNAMPTPARP1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |