Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027396 | 0.88 | NAMPT (0.41) | NAMPTGPR119ACACB | |
| SCHEMBL31027436 | 0.85 | NAMPT (0.41) | NAMPTCYP2C9ACACB | |
| SCHEMBL25228458 | 0.76 | KIT (0.44) | NAMPTGPR119ACACB | |
| SCHEMBL31027424 | 0.75 | OPRD1 (0.41) | NAMPTGPR119 | |
| SCHEMBL31027427 | 0.74 | NAMPT (0.49) | NAMPTGPR119CYP2C9 | |
| SCHEMBL25272218 | 0.69 | KIT (0.45) | NAMPTGPR119ACACB | |
| SCHEMBL8218920 | 0.68 | GPR119 (0.48) | NAMPTGPR119 | |
| SCHEMBL30901891 | 0.68 | NAMPT (0.37) | NAMPTGPR119CYP2C9ACACB | |
| SCHEMBL30901894 | 0.67 | MEN1 (0.38) | NAMPT | |
| SCHEMBL25277206 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |