Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027932 | 0.88 | ERN1 (0.44) | TDP1ALDH1A1TSHRERN1LMNA | |
| SCHEMBL5911741 | 0.76 | TDP1 (0.47) | TDP1L3MBTL1ALDH1A1TSHRCRHBP | |
| SCHEMBL28641417 | 0.73 | CRHBP (0.53) | TDP1ALDH1A1TSHRERN1CRHBP | |
| SCHEMBL11758012 | 0.73 | TDP1 (0.55) | TDP1L3MBTL1TSHRLMNAKMT2A | |
| SCHEMBL28892095 | 0.72 | ALDH1A1 (0.50) | TDP1L3MBTL1ALDH1A1CRHBPCRHR2 | |
| SCHEMBL27556654 | 0.71 | HPRT1 (0.54) | TDP1ALDH1A1TSHRCRHBPCRHR2 | |
| SCHEMBL28635053 | 0.70 | CRHBP (0.49) | TDP1ALDH1A1ERN1CRHBPCRHR2 | |
| SCHEMBL28646250 | 0.70 | CRHBP (0.49) | TDP1ALDH1A1ERN1CRHBPCRHR2 | |
| SCHEMBL28632790 | 0.70 | CRHBP (0.49) | TDP1ALDH1A1ERN1CRHBPCRHR2 | |
| SCHEMBL8654849 | 0.69 | TDP1 (0.65) | TDP1L3MBTL1ALDH1A1TSHRCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406041-A | Tazemetostat synthesis method | 沈阳药科大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118406041-A | Tazemetostat synthesis method | 沈阳药科大学 | 2024-07-30 | — | — | CN | disclosed |