Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 13/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635053 | 0.82 | CRHBP (0.49) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL28639689 | 0.81 | CRHBP (0.46) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL28641417 | 0.80 | CRHBP (0.53) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL28646250 | 0.80 | CRHBP (0.49) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL11623472 | 0.71 | CRHBP (0.64) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL31027926 | 0.70 | TDP1 (0.44) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL3317242 | 0.70 | CRHBP (0.77) | CRHBPCRHR2ALDH1A1TDP1ERN1 | |
| SCHEMBL27774760 | 0.69 | GPR35 (0.62) | CRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL15461976 | 0.68 | ALDH1A1 (0.69) | CRHBPCRHR2ALDH1A1TDP1 | |
| SCHEMBL5707253 | 0.67 | CRHBP (1.00) | CRHBPCRHR2ALDH1A1TDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493433-B | Benzopyrone derivative capable of serving as GPR35 receptor agonist, preparation method and application thereof | 泰州医药城国科化物生物医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-113493433-A | Benzopyrone derivative capable of being used as GPR35 receptor agonist, preparation method and application thereof | 泰州医药城国科化物生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |