Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027926 | 0.88 | TDP1 (0.44) | ERN1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL31863830 | 0.73 | CRHBP (0.54) | ERN1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL3956703 | 0.73 | CRHBP (0.54) | ERN1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29858616 | 0.73 | LMNA (0.47) | KMT2AMEN1LMNAHPGDMAPT | |
| SCHEMBL29192912 | 0.73 | HTT (0.44) | ERN1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL28646250 | 0.72 | CRHBP (0.49) | ERN1ALDH1A1TDP1 | |
| SCHEMBL8070346 | 0.71 | PDGFRB (0.55) | ALDH1A1KMT2AMEN1RAB9AHTT | |
| SCHEMBL27826601 | 0.71 | HTT (0.45) | ALDH1A1KMT2AMEN1HTTLMNA | |
| SCHEMBL2484847 | 0.70 | VCAM1 (0.57) | ERN1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL28641417 | 0.69 | CRHBP (0.53) | ERN1ALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406041-A | Tazemetostat synthesis method | 沈阳药科大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118406041-A | Tazemetostat synthesis method | 沈阳药科大学 | 2024-07-30 | — | — | CN | disclosed |