Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821334 | 0.92 | ITGB3 (0.43) | P2RY2CTSKAAK1ITGB3ITGA2B | |
| SCHEMBL24075680 | 0.84 | AAK1 (0.44) | CTSKATMMAPTKDM4EAAK1 | |
| SCHEMBL31028267 | 0.84 | P2RY2 (0.44) | P2RY2CTSKTDP1ATMNPSR1 | |
| SCHEMBL24075373 | 0.83 | LTA4H (0.36) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL31028260 | 0.80 | P2RY2 (0.40) | P2RY2CTSKTDP1NPSR1MAPT | |
| SCHEMBL28821349 | 0.76 | ITGB3 (0.42) | P2RY2CTSKAAK1ITGB3ITGA2B | |
| SCHEMBL31028274 | 0.76 | LMNA (0.36) | P2RY2TDP1ATMNPSR1MAPT | |
| SCHEMBL24074705 | 0.75 | MAPT (0.40) | TDP1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL20089226 | 0.72 | CTSK (0.47) | P2RY2CTSKTDP1ATMNPSR1 | |
| SCHEMBL17369171 | 0.71 | CTSK (0.49) | P2RY2CTSKTDP1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371434-B2 | MLL1 inhibitors and anti-cancer agents | CHINA NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH CO., LTD. (CN) | 2025-07-29 | — | — | US | disclosed |
| EP-4013754-B1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2024-07-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371434-B2 | MLL1 inhibitors and anti-cancer agents | MLLT1, BMI1, DOT1L | P2RY2 4298/4885CTSK 4303/4885TDP1 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.