Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 8/20 | 0.42 |
| ▸ | DRD4 | P21917 | 8/20 | 0.42 |
| ▸ | DRD3 | P35462 | 8/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28854769 | 0.83 | KDM1A (0.52) | GRIN1GRIN2BDRD2DRD4DRD3 | |
| SCHEMBL11493458 | 0.78 | CHRM2 (0.50) | ALDH1A1DRD2DRD4DRD3CHRM2 | |
| SCHEMBL31033189 | 0.77 | DRD2 (0.64) | ALDH1A1TP53GRIN1GRIN2BDRD2 | |
| SCHEMBL5234944 | 0.77 | BRPF1 (0.50) | ALDH1A1TP53MAPTDRD2DRD4 | |
| SCHEMBL31033213 | 0.76 | DRD2 (0.56) | ALDH1A1TP53GRIN1GRIN2BDRD2 | |
| SCHEMBL2674982 | 0.76 | DRD2 (0.66) | GRIN1GRIN2BDRD2DRD4DRD3 | |
| SCHEMBL31033146 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TP53DRD2DRD3TSHR | |
| SCHEMBL5025475 | 0.73 | MEN1 (0.53) | ALDH1A1TSHRBRPF1 | |
| SCHEMBL31033166 | 0.73 | DRD4 (0.52) | ALDH1A1TP53DRD2DRD4 | |
| SCHEMBL31033175 | 0.73 | TP53 (0.50) | ALDH1A1TP53MAPTDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |