Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033183 | 0.80 | KMT2A (0.56) | ALDH1A1TP53DRD2DRD3KMT2A | |
| SCHEMBL9368923 | 0.79 | PRMT5 (0.47) | PRMT5WDR77DRD2DRD3KMT2A | |
| SCHEMBL38653482 | 0.78 | PRMT5 (0.51) | PRMT5WDR77KMT2AGRM5 | |
| SCHEMBL9023866 | 0.78 | PRMT5 (0.46) | PRMT5WDR77DRD2DRD3KMT2A | |
| SCHEMBL9024811 | 0.77 | PRMT5 (0.46) | PRMT5WDR77ALDH1A1DRD2DRD3 | |
| SCHEMBL11985664 | 0.75 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL9024164 | 0.75 | SIGMAR1 (0.50) | TP53KMT2A | |
| SCHEMBL9024576 | 0.74 | SIGMAR1 (0.51) | TP53KMT2A | |
| SCHEMBL9369658 | 0.74 | DRD3 (0.67) | ALDH1A1DRD2DRD3 | |
| SCHEMBL28823671 | 0.74 | PRMT5 (0.48) | PRMT5WDR77KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |