Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985664 | 0.84 | PRMT5 (0.49) | PRMT5WDR77ROCK2ROCK1MAPK1 | |
| SCHEMBL38653482 | 0.80 | PRMT5 (0.51) | PRMT5WDR77KCNH2KMT2APKM | |
| SCHEMBL23160605 | 0.75 | PRMT5 (0.47) | PRMT5WDR77ROCK2ROCK1TNIK | |
| SCHEMBL23160686 | 0.75 | PRMT5 (0.47) | PRMT5WDR77ROCK2ROCK1TNIK | |
| SCHEMBL9368923 | 0.75 | PRMT5 (0.47) | PRMT5WDR77SCN1ASCN4AKCNH2 | |
| SCHEMBL31033174 | 0.74 | PRMT5 (0.49) | PRMT5WDR77KMT2A | |
| SCHEMBL9023866 | 0.74 | PRMT5 (0.46) | PRMT5WDR77KMT2APKMTSHR | |
| SCHEMBL9024811 | 0.73 | PRMT5 (0.46) | PRMT5WDR77KMT2A | |
| SCHEMBL29877570 | 0.73 | ROCK2 (0.70) | ROCK2ROCK1TNIK | |
| SCHEMBL16546168 | 0.71 | PKM (0.44) | PRMT5WDR77KMT2APKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |