SCHEMBL28538693

SCHEMBL28538693

O=C(O)CN(CO)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.43
CAMK2A Q9UQM7 1/20 0.43
CYP1A1 P04798 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA3 P07451 1/20 0.38
TYR P14679 1/20 0.38
DRD1 P21728 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 3/20 0.36
ESRRG P62508 3/20 0.36
POLB P06746 2/20 0.36
GAA P10253 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13645018 0.91 CA2 (0.46) CA2CAMK2ACYP1A1CA12CA1
SCHEMBL8483627 0.84 ESRRG (0.48) CA2CAMK2ATDP1ALDH1A1ESRRG
SCHEMBL547411 0.83 TDP1 (0.47) TDP1ALDH1A1POLBGAAL3MBTL1
SCHEMBL13644973 0.82 CA2 (0.42) CA2CAMK2ACYP1A1CA12CA1
SCHEMBL8038936 0.82 TDP1 (0.44) DRD1TDP1ALDH1A1KDM4EBLM
SCHEMBL2985103 0.80 CA2 (0.37) CA2CAMK2ACYP1A1CA12CA1
SCHEMBL11297196 0.78 CA2 (0.46) CA2CAMK2ACYP1A1CA12CA1
SCHEMBL13645000 0.78 CYP1A1 (0.41) CA2CAMK2ACYP1A1ALDH1A1ESRRG
SCHEMBL13603850 0.78 ALDH1A1 (0.40) CA2CAMK2ACYP1A1CA12CA1
SCHEMBL7643003 0.77 PLA2G2A (0.46) ALDH1A1ESRRGPOLBGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109400491-B Crystallization preparation method of L-p-hydroxyphenylglycine methyl ester 威海海洋职业学院 2021-03-23 CN claimed