Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 9/20 | 0.51 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034527 | 0.86 | TAS2R14 (0.60) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL29671340 | 0.85 | APLNR (0.61) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL27020194 | 0.83 | TAS2R14 (0.59) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL24472769 | 0.82 | HDAC6 (0.77) | HDAC6HDAC11HDAC8TAS2R14CXCR3 | |
| SCHEMBL31034590 | 0.81 | APLNR (0.50) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL31034596 | 0.80 | APLNR (0.52) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL31034592 | 0.80 | APLNR (0.52) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL29665682 | 0.79 | APLNR (0.54) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL31034551 | 0.78 | APLNR (0.56) | HDAC6HDAC11HDAC8TAS2R14APLNR | |
| SCHEMBL22483037 | 0.77 | HDAC8 (0.58) | HDAC6HDAC11HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |