Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TERT | O14746 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386027 | 0.85 | NLRP3 (0.51) | NLRP3KDM4EALDH1A1HPGDTERT | |
| SCHEMBL10998887 | 0.82 | CYP1A2 (0.52) | NLRP3KDM4EALDH1A1HPGDTERT | |
| SCHEMBL31312543 | 0.76 | TERT (0.76) | KDM4EALDH1A1HPGDTERT | |
| SCHEMBL18687248 | 0.76 | MAPT (0.76) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL14566624 | 0.75 | LMNA (0.53) | NLRP3MAPTMEN1LMNAKMT2A | |
| SCHEMBL11548746 | 0.75 | PSMB8 (0.54) | NLRP3KDM4EALDH1A1HPGDTERT | |
| SCHEMBL10386822 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDTERTMAPT | |
| SCHEMBL31035886 | 0.72 | MAPT (0.68) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL31036001 | 0.71 | NOTUM (0.59) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL26280001 | 0.71 | LMNA (0.45) | NLRP3KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |