Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.44 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386027 | 0.89 | NLRP3 (0.51) | PSMB8ALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL11551548 | 0.84 | KDM4E (0.54) | PSMB8ALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL13015583 | 0.79 | ADORA3 (0.51) | PSMB8LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL27056782 | 0.78 | PSMB8 (0.51) | PSMB8LRRK2SMN1; SMN2LMNABRD4 | |
| SCHEMBL11545418 | 0.77 | SMN1; SMN2 (0.74) | ALDH1A1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL12207033 | 0.76 | PSMB8 (0.49) | PSMB8LRRK2ALDH1A1LMNABRD4 | |
| SCHEMBL10386822 | 0.76 | KDM4E (0.57) | ALDH1A1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL12361997 | 0.76 | LMNA (0.53) | PSMB8LRRK2MEN1KMT2ALMNA | |
| SCHEMBL9508666 | 0.76 | MAPT (0.57) | ALDH1A1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL1152724 | 0.76 | MAPT (0.61) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |