Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773573 | 0.87 | RECQL (0.57) | RECQLL3MBTL1TRPV1HPGDALDH1A1 | |
| SCHEMBL3919664 | 0.85 | TRPV1 (0.71) | RECQLL3MBTL1TRPV1HPGDALDH1A1 | |
| SCHEMBL31035980 | 0.83 | TRPV1 (0.73) | RECQLL3MBTL1TRPV1HPGDALDH1A1 | |
| SCHEMBL31036003 | 0.83 | TRPV1 (0.73) | RECQLL3MBTL1TRPV1HPGDALDH1A1 | |
| SCHEMBL31035861 | 0.83 | TRPV1 (0.73) | RECQLL3MBTL1TRPV1HPGDALDH1A1 | |
| SCHEMBL7598872 | 0.83 | L3MBTL1 (0.74) | RECQLL3MBTL1TRPV1HPGDALDH1A1 | |
| SCHEMBL154367 | 0.80 | MTNR1A (0.73) | L3MBTL1HPGDALDH1A1MTNR1AMTNR1B | |
| Benzene SCHEMBL29176463 | 0.80 | MTNR1A (0.73) | L3MBTL1HPGDALDH1A1MTNR1AMTNR1B | |
| SCHEMBL553140 | 0.78 | PLAAT3 (0.50) | L3MBTL1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL25139566 | 0.78 | L3MBTL1 (0.66) | RECQLL3MBTL1TRPV1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |