SCHEMBL31037498

SCHEMBL31037498

CCC(=O)Nc1ccc(NC(=O)NCCc2cccnc2)cc1C#Cc1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.44
▸ NAMPT P43490 12/20 0.44
▸ PRMT3 O60678 1/20 0.43
▸ POLB P06746 1/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037483 0.89 NAMPT (0.47) LMNANAMPTPRMT3
SCHEMBL31037293 0.85 LMNA (0.48) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037286 0.85 LMNA (0.48) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037322 0.84 HDAC2 (0.43) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037328 0.84 NAMPT (0.46) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037302 0.83 NAMPT (0.51) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037349 0.81 NAMPT (0.42) LMNANAMPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL31037468 0.79 LMNA (0.44) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037254 0.79 NAMPT (0.46) LMNANAMPTPRMT3L3MBTL1SMN1; SMN2
SCHEMBL31037327 0.79 PRMT3 (0.55) LMNANAMPTPRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 — — EP disclosed
WO-2024166024-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2024-08-15 — — WO disclosed
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