Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 4/20 | 0.62 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037843 | 0.90 | DHPS (0.52) | DHPSPDE2AALOX5ADORA3HTT | |
| SCHEMBL7854304 | 0.87 | DHPS (0.49) | DHPSADORA1HTTLMNATSHR | |
| SCHEMBL31037849 | 0.87 | DHPS (0.49) | DHPSPDE2AALOX5HTTALDH1A1 | |
| SCHEMBL31037845 | 0.85 | HTR6 (0.46) | DHPSADORA3ADORA1HTTALDH1A1 | |
| SCHEMBL31037801 | 0.82 | DHPS (0.82) | DHPSPDE2AADORA3ADORA1MAPK1 | |
| SCHEMBL31037839 | 0.82 | DHPS (0.43) | DHPSHTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL31037840 | 0.81 | DHPS (0.48) | DHPSALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL31037844 | 0.81 | DHPS (0.43) | DHPSALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL7483960 | 0.79 | HTT (0.48) | DHPSHTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5632966 | 0.78 | HTT (0.47) | DHPSHTTALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | disclosed |