Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037845 | 0.89 | HTR6 (0.46) | DHPSL3MBTL1ALDH1A1TSHRTDP1 | |
| SCHEMBL31037839 | 0.85 | DHPS (0.43) | DHPSKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL31037817 | 0.84 | DHPS (0.57) | DHPSKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL31037840 | 0.84 | DHPS (0.48) | DHPSKMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL31037841 | 0.81 | DHPS (0.62) | DHPSL3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL31037800 | 0.79 | DHPS (0.71) | DHPS | |
| SCHEMBL31037843 | 0.77 | DHPS (0.52) | DHPSL3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL31037824 | 0.77 | DHPS (0.74) | DHPS | |
| SCHEMBL7483960 | 0.75 | HTT (0.48) | DHPSL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL31037849 | 0.74 | DHPS (0.49) | DHPSKMT2AL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666758-A | Anti-melanoma benzyl pyrimidine compound and preparation method and application thereof | 中国医科大学附属盛京医院 | 2024-09-20 | — | — | CN | disclosed |