Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320016 | 0.93 | SMN1; SMN2 (0.55) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL31726707 | 0.93 | SMN1; SMN2 (0.55) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL31727301 | 0.89 | SMN1; SMN2 (0.56) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL31727280 | 0.89 | SMN1; SMN2 (0.56) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL18428244 | 0.88 | JAK2 (0.52) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL18477527 | 0.87 | FKBP1A (0.52) | TMEM97SIGMAR1FKBP1APREP | |
| SCHEMBL13954406 | 0.86 | GPR119 (0.67) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL2960273 | 0.84 | PREP (0.57) | FKBP1APREP | |
| SCHEMBL1586077 | 0.84 | JAK2 (0.55) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL8569488 | 0.84 | CCR5 (0.53) | GPR119SMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714446-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-03-25 | — | — | EP | disclosed |
| EP-4413985-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-08-14 | — | — | EP | disclosed |